The neurobiology of autism spectrum disorder remains poorly understood. The present study addresses this knowledge gap by examining the relationship between functional brain connectivity and Autism Diagnostic Observation Schedule (ADOS) scores using publicly available data from the Autism Brain Imaging Data Exchange (ABIDE) database (N = 107).…

New brain imaging methods are helping us better understand how children learn, writes neuroscientist John Gabrieli. But "education neuroscience" has become the source of both promise and debate.

Behavioral flexibility is important in a changing environment. Previous research suggests that systems consolidation, a long-term poststorage process that alters memory traces, may reduce behavioral flexibility. However, exactly how systems consolidation affects flexibility is unknown. Here, we tested how systems consolidation affects: (1)…

Learning and memory involves a large neural network of many brain regions, including the notable hippocampus along with the retrosplenial cortex (RSC) and lateral septum (LS). Previous studies have established that the dorsal hippocampus (dHPC) plays a critical role during the acquisition and retrieval/expression of episodic memories. However, the…

An essential feature of episodic memory is the ability to recall the multiple elements relating to one event from the multitude of elements relating to other, potentially similar events. Hippocampal pattern separation is thought to play a fundamental role in this process, by orthogonalizing the representations of overlapping events during…

Growth hormone (GH) deficiency is associated with cognitive decline which occur both in normal aging and in endocrine disorders. Several brain areas express receptors for GH although their functional role is unclear. To determine how GH affects the capacity for learning and memory by specific actions in one of the key areas, the hippocampus, we…

Emerging literature links neighborhood disadvantage to altered neural function in regions supporting socioemotional and threat processing. Few studies, however, have examined the proximal mechanisms through which neighborhood disadvantage is associated with neural functioning. In a sample of 7- to 19-year-old twins recruited from disadvantaged…

The effect of first language transfer on second language acquisition and learning has been a major theoretical concept in second language research and pedagogy since the 1950s. In order to give a historical perspective, the authors offer a brief presentation of some of the major topics from the broad spectrum of issues that have been examined by…

Embodied models of language comprehension assume that words become associated with sensorimotor experiences during word learning. Novel word learning paradigms may provide insight into embodied effects, but studies in this domain have yet to account for how concepts and information known in first language (L1) might influence the sensorimotor…

In this beautifully-written book, the authors skip across the many bridges that connect neuroscience to education, creating a wonderful resource for educators. They consider all the elements that an understanding of neuroscience can bring to education in a highly accessible manner, focusing on emotions and spiritual meaning as well as more…

Protein kinase M[zeta] (PKM[zeta]) maintains long-term potentiation (LTP) and long-term memory through persistent increases in kinase expression. Early-life adversity is a precursor to adult mood and anxiety disorders, in part, through persistent disruption of emotional memory throughout life. Here we subjected 10- to 16-wk-old male bonnet…

For more than a half-century, lists of words have served as the memoranda of choice in studies of human memory. To better understand why some words and lists are easier to recall than others, we estimated multivariate models of word and list recall. In each of the 23 sessions, subjects (N = 98) studied and recalled the same set of 576 words,…

Negation is known to have inhibitory consequences for the information under its scope. However, how it produces such effects remains poorly understood. Recently, it has been proposed that negation processing might be implemented at the neural level by the recruitment of inhibitory and cognitive control mechanisms. On this line, this manuscript…

Purpose: Atypical pragmatic language can impede quality health care access. Right hemisphere brain damage (RHD) results in changes in pragmatic language use; however, little is known about whether there are racial/ethnic influences. Recent research indicated differences in question-asking when RHD survivors were compared with healthy controls,…

This triple-arm, double-blind, randomized clinical trial investigated the effect of multisession prefrontal transcranial direct current stimulation (tDCS) on social functioning in individuals with autism spectrum disorder (ASD). A total of 105 individuals (age 14-21 years) diagnosed with ASD were randomized into the active-tDCS, sham-tDCS, and…