Catatonia is a severe clinical syndrome which has been increasingly reported in autism spectrum disorder (ASD). The prevalence of catatonia in ASD is unknown. Diagnosing catatonia in ASD is complicated by overlapping clinical features such as mutism, stereotypies, and echophenomena. Here, we present the clinical histories of two individuals with…

Objective: Describe the frequency and characteristics of unclaimed prescriptions from a pharmacy embedded within a student health services clinic. Methods: Cross-sectional study of prescriptions received by an on-campus pharmacy between September 1-December 31, 2017 and September 1-December 31, 2018. Prescription data were extracted from the…

To evaluate effects of psychotropic medication for children with disabilities, direct assessments may offer a valuable supplement to caregiver reports. Relative to indirect assessment, direct measures of behavior can increase objectivity and sensitivity, and some have potential to isolate distinct behavioral and learning processes. We conducted a…

Background: As health systems face increasing demands, non-medical prescribing is a workforce redesign strategy adopted within some services. Despite successful implementation in other professional groups, non-medical prescribing within speech pathology (SP) has not yet been described. Aims: To provide a descriptive account of the development and…

U.S. consumers are spending billions on complementary and alternative medicines, and nearly half of those consumers on psychiatric prescription drugs also use herbal remedies. Clients may take herbaceuticals, over-the-counter drugs, and dietary supplements instead of, or in combination with, prescription drugs. This frequently occurs without the…

Background: The shortage of prescription stimulants is an ongoing issue that is impacting the ability of individuals with ADHD to access their medication. Amidst concerns that this shortage may have a substantial impact on individuals' ability to manage their symptoms effectively, this research seeks to understand the experiences and consequences…

Introduction: Conflicting findings exist regarding the link between attention deficit hyperactivity disorder (ADHD) and cardiovascular diseases. This study aimed to evaluate the frontal QRS-T (fQRS-T) angle and its correlation with symptom severity in children diagnosed with ADHD. Methods: The study population consisted of 172 patients diagnosed…

DockIT is an interactive molecular docking tool suitable for teaching students about concepts related to drug-receptor interaction. Its most unique feature is the ability to model both local and global conformational change in the receptor based on information derived from the trajectory of a molecular dynamics (MD) simulation. The workshop…

Autistic people with intellectual disabilities appear to be at increased risk of schizophrenia. While current recommendations emphasize adapting interventions used for people with schizophrenia in general, few studies to date have investigated treatment of co-occurring schizophrenia in this specific population. To explore what interventions are…

Applied behavioral pharmacology explores how drugs may influence problem behavior in persons with intellectual and developmental disability (IDD). A comprehensive review was conducted featuring single-case experimental designs in the domain of applied behavioral pharmacology to evaluate and report on study quality. Studies included in the review…

According to the active system consolidation theory, memory consolidation during sleep relies on the reactivation of newly encoded memory representations. This reactivation is orchestrated by the interplay of sleep slow oscillations, spindles, and theta, which are in turn modulated by certain neurotransmitters like GABA to enable long-lasting…

The focus of this study was to examine the status of medical cannabis instruction in counselor education curriculum programs. There is evidence to indicate that medical cannabis use may be beneficial in mental health care. However, there is limited research on medical cannabis in counselor education. The following research questions provided a…

Drug repurposing refers to the process of discovering new therapeutic uses for existing medicines. Compared to traditional drug discovery, drug repurposing is attractive for its speed, cost, and reduced risk of failure. However, existing approaches for drug repurposing involve complex, computationally-intensive analytical methods that are not…

Some patients benefit from a treatment while others may do so less or do not benefit at all. We have previously developed a two-stage network meta-regression prediction model that synthesized randomized trials and evaluates how treatment effects vary across patient characteristics. In this article, we extended this model to combine different…

Introduction: As little is known about who uses specialty mental health clinics for persons with intellectual disabilities, this study aimed to identified caregiver concerns, clinical characteristics, and the relationship between these two constructs for referrals to such a clinic. Methods: Qualitative and quantitative analyses were applied to…