The Minangkabau and the Dayak Kanayatn are two sub-ethnic groups in the Indonesian archipelago with both similar and diverse traditions, customs, moral values and in terms of anthropolinguistic and language aspects. This study aimed to examine the similarities and differences between the Minangkabau and the Dayak Kanayatn. Descriptive qualitative and comparative methods were used to analyse the data. Based on the results, it was found that Minangkabau ethnic group still adhered to their customs and culture, while the Dayak Kanayatn believed in supernatural powers (animism and dynamism) and upholds their traditional values. Hence, the two are similar in terms of traditions and customs, while the differences are based on the concept of divinity. Minangkabau is based on Islamic teachings, while Dayak Kanayatn is based on non-Islamic teachings. Another finding is the language similarity between Minangkabau and Dayak Kanayatn. These similarities are in morphological systems in which both have a morpheme or prefix {ba} which means 'ber' in the Indonesian language or 'to' in English and a morpheme or prefix {sa} 'se' which means a number/as much; preposition (preposition) ka 'to'; and lexical equations. This study provides useful insights for further research.