An efficient synthesis of the exorbitantly priced Lambert-Eaton myasthenic syndrome drug amifampridine was developed and applied in the second-semester undergraduate organic chemistry laboratory. The two-step synthesis entails a nucleophilic aromatic substitution reaction of commercial 4-chloro-3-nitropyridine with methanolic ammonia to afford…

In view of the mounting requirements for courses in nuclear chemistry and radiochemistry, hands-on experience in the separations of radioisotopes is imperative. Three separation techniques commonly used were introduced, coprecipitation, liquid-liquid extraction, and ion-exchange chromatography. Their principles and the associated fundamental…

In chemistry, a eutectic mixture refers to a mixture of two or more components at which the lowest possible freezing point is observed. This phenomenon is covered in a wide range of curricula such as physics, chemistry, chemical engineering, and pharmacy to various depths. Despite the significance of this phenomenon in pharmaceutical compounding…

For decades, chemical modeling sets have allowed the user to manipulate atoms and bonds using plastic/wooden ball and stick materials. Here is a design for an interlocking toy brick modeling set in which the undergraduate nursing student can manipulate electrons during the simulated chemical bonding exercise. The author presents a teaching and…

A multioutcome, discovery-based column (CC) and thin layer chromatography (TLC) experiment has been designed for introductory organic chemistry. Multiple outcomes were established using commercially available two- and three-component analgesic medications based on acetaminophen, acetylsalicylic acid (aspirin), and ibuprofen. A series of 11…

The pharmacologically active lignans sesamin and sesamolin are minor components of sesame oil and ingredients in OTC dietary supplement capsules. We report an introductory undergraduate organic laboratory experiment combining natural product isolation and spectral analysis in which students isolate a mixture of sesamin and sesamolin by either (1)…

Hydrogels are soft water-rich materials with physical properties that can be easily tuned by modifying their network structure. For instance, increasing or decreasing the cross-linking density has a profound effect on their water absorption capabilities and mechanical strength. These physical changes are showcased in a new experiment for organic…

The process of diffusion is intimately related to random molecular displacement and is central to many problems in chemistry. Here, we provide an intuitive derivation of the diffusion equation based on the analysis of the random trajectories of particles generated and plotted by simple MATLAB and Python scripts. The codes are very simple and…

Artificial intelligence (AI) technology has the potential to revolutionize the education sector. This study sought to determine the efficacy of ChatGPT to correctly answer questions a learner would use and to elucidate how the AI was processing potential prompts. Our goal was to evaluate the role of prompt formats, response consistency, and…

The COVID-19 pandemic has displayed new challenges for chemistry instructors and students worldwide. An essential part of learning chemistry involves interactions in a laboratory ambiance. However, nowadays, it is necessary to consider alternatives to teaching experimental chemistry in an online environment. As a course project proposal, the…

Enzyme-like catalysis is the use of artificial catalysts to catalyze chemical reactions, which has the characteristics of enzymatic catalysis, such as high selectivity, high efficiency, and mild reaction conditions. In recent years, 2D materials, thickness ranging from a single to several atomic layers, have become a hot research topic in the…

In today's global economy, the origin of the food we eat is becoming more and more difficult to identify. Verifying the authenticity of products to protect supply chains is a complicated problem that requires a multidisciplinary approach. Chemical authentication of foodstuffs often includes a mass spectrometer detector; however, they are costly…

Inquiring about students' learning and their difficulties understanding the concepts and models of physics is a familiar challenge in physics education research. Researchers have developed various methodologies, such as phenomenography, to address it. Phenomenography is an empirical approach to determining how people experience and understand…

[This paper is part of the Focused Collection on Qualitative Methods in PER: A Critical Examination.] Qualitative research methods have provided key insights in physics education research (PER) by drawing on non-numerical data such as text or video data. While different methods towards qualitative research exist, they share two essential steps:…

We conducted a study with introductory and upper-division physics students in a Mexican university to learn how students independently recognize the electric field's main characteristics in the electric field lines diagram and as a source or target representation in conversion processes. We used the theory of registers of semiotic representations…