Imagination is necessary for scientific practice, yet there are no in vivo sociological studies on the ways that imagination is taught, thought of, or evaluated by scientists. This article begins to remedy this by presenting the results of a qualitative study performed on two systems biology laboratories. I found that the more advanced a…

A method for the synthesis of flufenamic acid, a nonstereoidal anti-inflammatory drug (NSAID) of the anthranilate family (fenams), is described as an experiment for the upper-division undergraduate organic chemistry laboratory. The key step is the formation of the diarylamine moiety of flufenamic acid by a novel reaction consisting of the coupling…

Analysis of collisions is standardly included in the introductory physics course. In one dimension (1D), there do not seem to be any unusual issues: Typically, the initial velocities of the two colliding objects are specified, and the problem is to find the final velocities. In 1D there are therefore two unknown variables. One can write the…

An upper-division undergraduate- or graduate-level laboratory experiment, challenging students to identify bovine serum albumin, equine myoglobin, bovine calmodulin, and bovine cytochrome c, uses four methods of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS): linear positive, in-source decay, peptide…

X-ray fluorescence is subject to significant matrix effects, which must be corrected in order to obtain accurate quantitative results. These are due to both absorption and enhancement effects, which are a consequence of the fact that both the analyte and the matrix absorb and fluoresce in the X-ray region, and this affects the magnitude of the…

Although kinetics forms a foundational part of the chemical curriculum, laboratory experiences with the subject are often limited and lack relevance to the actual practice of chemistry. Presented is an inquiry-based lab focused on Michaelis-Menten kinetics, implemented in an upper-level, university physical chemistry laboratory. Student learning…

The Leidenfrost nanochemistry synthesis of gold colloids was introduced in this "Journal" as an advanced method to synthesize gold nanoparticles during an undergraduate nanochemistry research project. When trying to repeat these experiments in the laboratory, we experienced difficulties in the synthesis of the gold nanoparticles since…

Cell migration, a fundamental process in development, wound healing, and immune function, is a common topic in undergraduate cell biology courses. We developed laboratory exercises with an inquiry-based learning (IBL) approach in which cell migration could be examined with the scratch assay, adapted from the primary literature. A narrow scratch…

Digitally simulated laboratory assessments (DSLAs) may be used to measure competencies such as problem solving and scientific inquiry because they provide an environment that allows the process of learning to be captured. These assessments provide many benefits that are superior to traditional hands-on laboratory tasks; as such, it is important to…

Calls for reform to instructional labs mean many instructors and departments are facing the daunting task of identifying goals for their introductory lab courses. Fortunately, the American Association of Physics Teachers (AAPT) released a set of recommendations for learning goals for the lab to support lab redevelopment. Here we outline the…

BYOL (Bring Your Own Lime), a novel laboratory experiment, is introduced in this paper. Students are encouraged to bring affordable household and grocery store chemicals into the classroom. The Bring Your Own Chemical (BYOC) concept demonstrates to students that food and household products are chemicals too. Citruses are often used to highlight…

The cardiovascular responses to exercise are mediated by several interactive neural mechanisms, including central command, arterial baroreflex, and skeletal muscle mechano- and metaboreflex. In humans, muscle metaboreflex activation can be isolated via postexercise ischemia (PEI), which increases sympathetic nerve activity and partially maintains…

This article argues that we need to make use of our everyday experiences when introducing concepts in chemistry that are often obscure. It uses reaction rates as an example and explores a common misconception related to the explanation of the effect of rising temperature on the rate of slow reactions.

Colleges and universities are learning to provide relevant virtual lab experiences for students due to the COVID-19 pandemic. Even schools attempting in-person instruction often need to utilize virtual experiences for students absent due to quarantine or illness. Much of biochemistry is amenable to molecular visualization and/or computational…

Models are at the heart of any physics discipline, and in recent decades physics education has shifted heavily toward teaching students how to think using models. Involving students in an investigation of a real phenomenon through measurements and the applications of models is an ideal learning experience for a physics student and is the aim of…