Quantum dots (QDs) are useful for demonstrating the particle-in-a-box (PIB) model utilized in quantum chemistry, and can readily be applied to a discussion of both thermodynamics and kinetics in an undergraduate laboratory setting. Modifications of existing synthetic procedures were used to create QDs of different sizes and compositions (CdS…

This experiment prepares a large (M[subscript r]: 1821 g mol[superscript -1]) triple helicate complex quickly in one pot from inexpensive starting materials. The protocol illustrates the power of self-assembly in a simple manner that is suitable for second-year general chemistry students using reversible imine bond and metal-ligand bond formation.…

In this laboratory experiment, students performed thermogravimetric analysis (TGA) coupled with mass spectrometry (MS) of herbaceous materials (TGA-MS) and learned to analyze mass-loss curves, as well as identify common fragmentation ions. The experiment is the first one to present the application of TGA in a currently relevant topic: biomass…

Performing the identification of organic chemical compounds from a set of spectroscopic data gives the opportunity to students to develop critical thinking and problem-solving skills. In this context, we developed a student-centered methodology for teaching molecular structural analysis to first-year undergraduate students. This systematic…

One challenge of teaching chemical analysis is the proliferation of sophisticated, but often impenetrable, instrumentation in the modern laboratory. Complex instruments, and the software that runs them, distance students from the physical and chemical processes that generate the analytical signal. A solution to this challenge is the introduction…

This paper summarizes a project seminar in analytical chemistry that includes a method comparison approach and collaborative learning. In this project seminar, 12 students worked in four groups, each of which focused on one method for quantitative element analysis, including flame atomic absorption spectroscopy, inductively coupled plasma mass…

Low cost, open-source analytical instrumentation has the potential to increase educational outcomes for students and enable large-scale citizen science projects. Many of these instruments rely on smartphones to collect the data, mainly because they can effectively leverage a dramatic price-to-performance ratio of the optical sensors. However,…

In an effort to repurpose expired guaifenesin tablets, experiments devised for practical instruction are reported for the preparation and isolation of the guaifenesin acetonide using a microscale kit. The laboratory experiment successfully utilizes a waste chemical in lieu of a fine chemical to illustrate the principles behind protecting groups in…

An organic chemistry experiment is described that is based on recent research to elucidate a novel cation-pi interaction between tetraalkammonium cations and propargyl hydrazines. This nonbonded interaction is a key component of the mechanism of ammonium-catalyzed intramolecular cycloaddition of nitrogen to the terminal carbon of a C-C triple bond…

Fundamental quantum chemistry concepts--quantization of energy, electronic structure, and light-matter interaction--are essential for understanding chemistry and spectroscopy, an important tool for studying molecules. However, very few studies have investigated how students learn and understand these concepts or how their learning can be…

Functional near-infrared spectroscopy (fNIRS) is an easy to use neuroimaging technique that is portable and maintains a liberal tolerance to movement. As such, fNIRS represents an ideal tool to observe children's neural activity as they engage in real-world classroom activities, such as the interaction with digital math apps on an iPad. Here, we…

Instructional videos have been prepared using Adobe Captivate software to create animated tutorials to capture instrument and molecular modeling software simulations and to allow for increased independent hands-on instrument use by students and faster training for instructors and teaching assistants. The videos are available on YouTube and can be…

Continued human and animal research has strengthened evidence for aberrant excitatory-inhibitory neural processes underlying autism and schizophrenia spectrum disorder psychopathology, particularly psychosocial functioning, in clinical and nonclinical populations. We investigated the extent to which autistic traits and schizotypal dimensions were…

In this experiment, the students explore the synthesis of a crystalline solid-state material, barium zirconate (BaZrO3) by two different synthetic methods: (a) the wet chemical method using BaCl[subscript 2]·2H[subscript 2]O and ZrOCl[subscript 2]·8H[subscript 2]O as the precursors, and (b) the solid-state reaction from BaCO[subscript 3] and…

In this experiment for an introductory undergraduate organic chemistry lab, students tetraalkylate tertbutylcalix[4]arene, a bowl-shaped macrocyclic oligophenol, and examine the supramolecular chemistry of the tetraether product by proton nuclear magnetic resonance (NMR) spectroscopy. Complexation with a sodium ion reduces the conformational…