This paper reports an innovative, hybrid teaching model for a junior level lab course. This model leverages in-person lab operation by adding a student-led online learning mode. Both course outcomes and student outcomes were evaluated. Student feedback was collected, and its analysis showed both positive and negative impacts in this hybrid model.…

A problem-based learning (PBL) methodology was implemented to a project, whose main objectives were to discuss and apply the Twelve Principles of Green Chemistry to the study of poly(vinyl alcohol)'s cross-linking reaction with dicarboxylic acids. The five participating students were oriented to be responsible for their own learning and the…

The COVID-19 outbreak has created turbulence and uncertainty into multiple aspects of life in countries around the world. In China, the pandemic continues to pose a great challenge to the nature of traditional in-class education in schools. Chinese education has faced the difficult decision of whether to resume in-person teaching in an…

The nature of science describes what science is, how it works, and its interactions with society under the perspectives of philosophy, history, sociology, and psychology of science. Understanding it is an essential aspect of scientific literacy. Given the critical role that school textbooks hold, considering what is taught and how it is taught in…

Research-based blended learning (RBBL) allows students to be part of an authentic scientific discovery process. In this study, students' perception and motivation of the RBBL coupled with Scrum methodology in a third-year polytechnic chemistry laboratory course were investigated. Results showed that the scaffolded approach, designed referencing…

In this paper we designed a STEM outreach program with a modular tissue engineering education tool (we refer to as "modular cyclic-stretch device") to engage high school students in STEM hands-on activities. Using simple machines such as gears and rotating cams, students were able to build a custom device to apply cyclic stretch to…

X-ray crystallography provides structural information of molecules at the atomic level, being a central technique at the forefront of science and technology. However, crystallography teaching is not usually implemented in biochemistry lab classes due to its complex execution by nonexpert users. Here, we report the basic step-by-step workflow…

This laboratory experiment, designed for undergraduate nonmajors or advanced high school students, attempts to demystify the technique of spectrophotometry by utilizing a hands-on, real-world approach. Modification of the reaction for the formation of Fe[(bpy)[subscript 3]][subscript 2+] allows students to interact with vitamin C, a compound with…

Picture boards as a visual support aid for in-lab demonstrator briefings were deployed for a single experiment in both the first and second year undergraduate practical classes. The boards are easy to create and provide an alternative, more accessible and 'presentation friendly' perspective of the laboratory manual associated with an experiment.…

We devised an activity to explore friction by testing some of the common theories on how ancient Egyptians moved the stones used to build the pyramids. The activity is suitable for a high school physics course or introductory college courses for both science majors and non-science majors. The students investigate dragging a 1-kg mass (representing…

Laboratory kits allow students to take home laboratory equipment to complete experiments on their own time. Because of the lower cost, laboratory kits expand access to hands-on experiences for online courses and to budget-strapped campuses. Although students like laboratory kits, no previous studies compared student learning objectives on…

Flavonoids have been studied extensively for their antioxidant properties. Specifically, the flavonoids in tea, such as catechin and epigallocatechin gallate, have been shown to have positive health effects. These compounds are also oxidizable, so the concentrations of these compounds in a given kind of tea can be determined using cyclic…

This innovative comprehensive experiment is a compulsory course for third-year undergraduate students in the eight-year training program leading to a Doctor of Medicine degree or Doctor of Philosophy degree at Peking University Health Science Center (PKUHSC). There is a critical educational need to prepare these students for the increasing…

Frogs are routinely used in physiology teaching laboratories to demonstrate important physiological processes. There have been recent directives that promote the use of the anesthetic MS-222 (tricaine methanesulfonate), rather than lowering body temperature with a cold water bath to prepare reptiles and amphibians for physiological experiments or…

Metabolomics is the data-driven science of small molecules. Untargeted metabolomics, using liquid chromatography-high resolution mass spectrometry (LC-HRMS), differs greatly from targeted metabolite assays, using nominal mass LC-MS instruments, as it generates thousands of metabolite features which are not quantified and are identified "post…