HIV protease has served as a model protein for understanding protein structure, enzyme kinetics, structure-based drug design, and protein evolution. Inhibitors of HIV protease are also an essential part of effective HIV/AIDS treatment and have provided great societal benefits. The broad applications for HIV protease and its inhibitors make it a…

Electrospray ionization-mass spectrometry (ESI-MS) is a powerful technique for the detection, identification, and quantification of organic compounds. As mass spectrometers have become more user-friendly and affordable, many students--often with little experience in mass spectrometry--find themselves needing to incorporate mass spectrometry into…

This adaptable graduate laboratory course on protein purification offers students the opportunity to explore a wide range of techniques while allowing the instructor the freedom to incorporate their own personal research interests. The course design involves two sequential purification schemes performed in a single semester. The first part…

Research ability can be thought of as a competence, which requires other abilities -- both generic and specific -- to be successfully developed. In this study, we determine the degree of importance that the 21 specific competences (SCs) established in the Tuning Latin America (Tuning-LA) Project, have in the acquisition of research ability in…

Changes in the National Curriculum for England in 2014 included the introduction of levers, gears, and pulleys into primary science. Although simple mechanisms had been part of the design and technology (DT) curriculum for some time, it was the first time that the science behind the mechanisms had been included at the primary school level. These…

Third year chemical engineering undergraduate students at The University of Akron designed and fabricated a heat exchanger for a stirred tank as part of a Chemical Engineering Laboratory course. The heat exchanger portion of this course was three weeks of the fifteen week long semester. Students applied concepts of scale-up and dimensional…

The purpose of this study was to determine Primary Teacher Education (PTE) Trainees' perceptions regarding their preparedness to teach science in primary schools. A descriptive survey research design was used and stratified proportionate random sampling techniques used to select 177 males and 172 females. The study found out that more male trainee…

In this article, I introduce a framework for guiding future citizens to think critically about nature of science (NOS) and "with" NOS as they engage in socioscientific decision making. The framework, referred to as the critical thinking--nature of science (CT-NOS) framework, explicates and targets both NOS as a learning objective and NOS…

Situating science concepts in concrete and authentic contexts, using information and communications technologies, including multimodal modeling tools, is important for promoting the development of higher-order thinking skills in learners. However, teachers often struggle to integrate emergent multimodal models into a technology-rich informal…

It is known that experts identify or perceive meaningful patterns in visual stimuli related to their domain of expertise. This study explores the speed with which experts and novices detect changes in physics diagrams. Since change detection depends on where individuals direct their attention, differences in the speed with which experts and…

This paper describes the results of a qualitative study using ground theory to investigate the different approaches used by chemists when answering open-ended problems. The study involved undergraduate, industrialist and academic participants who individually answered three open-ended problems using a think aloud protocol. Open-ended problems are…

This study investigated the levels of possession of science process skills by final year Nigerian Certificate in Education (NCE) Students in colleges of Education in South-Eastern States of Nigeria. The skills that were assessed were observation, experimentation, measurement, communication, and inference. The research was guided by five research…

Explanation studies underlined the importance of using evidence in support of claims. However, few studies have focused on students' use of others' data (second-hand data) in this process. In this study, students collected data from a local water source and then took all the data back to the classroom to create scientific explanations by using…

An instrumentation-based laboratory curriculum combining traditional unknown analyses with student-designed projects has been developed for an introductory analytical chemistry course. In the first half of the course, students develop laboratory skills and instrumental proficiency by rotating through six different instruments performing…

Our out-of-school practical exercise was designed to bring upper secondary school students in contact with one of the most exciting and expanding topics in biology today: epigenetics. In school, students only study the basics in genetics and the respective investigation techniques as provided by the syllabus. For a practical exercise in…