The application of chemistry concepts in biological settings plays an important role in the interdisciplinary field of drug discovery and development. This is true for molecular docking, where an understanding of intermolecular forces and noncovalent interactions is useful for rational drug design and development. Here we report the design and use…

Structure--activity relationships are foundational concepts in biochemistry and drug design. Despite their importance, it can be difficult to create and execute laboratory activities that allow students to directly observe the interactions between small-molecule drugs and their biomolecular targets. Here, we report an activity that investigates…

Pharmaceutical Integrated Experiment (PIE) is a systematic and comprehensive compulsory course for undergraduates majoring in pharmacy and pharmaceutical engineering. This course mainly focuses on integrating the theoretical knowledge of various disciplines into practice, enabling students to master the key processes of drug research and…

Success in general chemistry requires active engagement with course material. COVID-19 accelerated the move to online courses, creating a crucial need for engaging course activities. The Mysterious Compound chemistry game was designed to engage undergraduate students in introductory chemistry concepts while allowing the instructor and students to…

A survey of Oregon State University Department of Chemistry personnel revealed that few of the faculty and graduate student respondents (only 6.7% and 8.3%, respectively) reported knowing the location of the automated external defibrillator (AED) nearest their workspace. Furthermore, a minority of both faculty and graduate student respondents…

Cycloadditions in combination with multicomponent reactions are among the most valuable synthetic tools used by organic chemists to construct cyclic and heterocyclic compounds in a straightforward way. Although cycloadditions, such as the Diels--Alder reaction, are mainly covered in basic and advanced organic courses for undergraduate students,…

Density functional theory (DFT) is indubitably the most popular and among the most successful approaches for approximately solving the many-electron Schro¨dinger equation. The level of understanding on the part of both researchers and students using DFT, however, is lacking, given the availability of black-box software. The present work addresses…

Text-to-speech (TTS) technology is a common accommodation available for students with disabilities. Despite the ubiquitous nature of TTS, this technology has not been explored in laboratory settings for neurodiverse college students. This study explores the adaptability of laboratory accessible TTS technology (originally developed for blind/low…

The COVID-19 pandemic has changed the way that students and educators are able to interact in higher education settings, and timely investigations into its impact on science, technology, engineering, and mathematics (STEM) students are of critical importance. In a continued effort to provide student data to chemistry educators, we offer a…

Many of the current synthetic methodologies utilized within academic and industrial laboratories require knowledge of how to safely handle air- and moisture-sensitive reagents and work under inert atmospheres. As a result, the ACS Committee on Professional Training recommends incorporating synthetic methods that make use of these inert atmospheres…

The paired-term biochemistry exam comprises five pairs of "unrelated" biochemical terms, where the collection of pairs, overall, is unique for each student. The student selects four of the pairs and answers three short essay questions about each, with a focus on how structure leads to function at the molecular level. Both…

When learning chemistry, students must learn to extract chemical information from mathematical expressions. However, chemistry students' exposure to mathematics often comes primarily from pure mathematics courses, which can lead to knowledge fragmentation and potentially hinder their ability to use mathematics in chemistry. This study examines how…

We report an educational tool for the upper level undergraduate quantum chemistry or quantum physics course that uses a symbolic approach via the PySyComp Python library. The tool covers both time-independent and time-dependent quantum chemistry, with the latter rarely considered in the foundations course due to topic complexity. We use quantized…

This paper uses the questionnaire to evaluate the current status of laboratory safety perceptions, willingness, and efforts of first-year undergraduates at the School of Chemistry and Chemical Engineering, Tianjin University of Technology. The survey includes a sample size of 360 undergraduates covering four chemistry-related majors. The…

Potassium tris(oxalato)ferrate(III) trihydrate is a commonly prepared coordination compound in general or upper-level chemistry laboratories and can be recycled to grow large single crystals that instructors may display when introducing the experiment to classes. Showing the crystal's shape can also be used to briefly introduce students to X-ray…