Scientific knowledge is tentative and open to revision. This sense of tentativeness, or changeability, is missing in the way textbooks and teachers often portray the nature of science (NOS). Instead, students are left with the impression that the scientific method produces sure knowledge and that they can uncritically accept the knowledge because…

This article presents an activity for early-in-the-year parents' night. The beginning of a new school year is an exciting time. The authors, as teachers, like to capture that excitement by engaging their 10th-grade biology students in an inquiry project demonstrating the nature of science and scientific inquiry. They developed the Next Step…

The desire to observe and understand the natural world is strong in young children, but high school students often consider science irrelevant to their daily lives. Therefore, as teachers of older age groups, the authors constantly struggle to engage students in scientific exploration so they can master concepts and appreciate the nature of…

In this article, the author discusses the CHANCE (Connecting Humans and Nature in the Costa Rican Environment) program, a coordinated effort between The Pennsylvania State University (PSU) and the Pennsylvania Department of Education that trains 9th- through 12th-grade teachers to be more like scientists and develop a unique, pedagogical tool for…

This paper describes the author's experience of designing and teaching an interdisciplinary course titled "Light", in collaboration with a visual artist. The goals of the course, texts used, laboratory work, art studio work, and other course activities are discussed with an emphasis on how light was used as a theme to make connections between…

This paper describes an easy experiment to study the absorption and action spectrum of photosynthesis, as well as the inhibition by heat, high light intensity and the presence of the herbicide 3-(3,4-dichlorophenyl)-1,1-dimethylurea (DCMU) on the photosynthetic process. The method involves measuring the chlorophyll fluorescence emitted by intact…

We describe a polymerase chain reaction (PCR) protocol suitable for use in secondary schools and colleges. This PCR protocol can be used to investigate genetic variation between plants. The protocol makes use of primers which are complementary to sequences of nucleotides that are highly conserved across different plant genera. The regions of…

This paper describes some simple and rapid techniques for examining the growth responses of fungal hyphae cultivated on environmental gradients. The creation of such gradients using agar-based growth media in petri dishes is explained, along with recommendations for quantitative macroscopic and microscopic measurements. The intention is to provide…

Lab safety begins with the teacher. Teachers must make learning how to be safe an integral and important part of their professional development and work. Teachers who are unfamiliar with laboratory instruction should take whatever steps necessary to prepare for the unique challenges associated with safety in conducting laboratory investigations…

Stress facilitates memory formation, but only when the stressor is closely linked to the learning context. These effects are, at least in part, mediated by corticosteroid hormones. Here we demonstrate that corticosterone rapidly facilitates synaptic potentiation in the mouse hippocampal CA1 area when high levels of the hormone and high-frequency…

Cannabinoid receptors type 1 (CB1) play a central role in both short-term and long-term extinction of auditory-cued fear memory. The molecular mechanisms underlying this function remain to be clarified. Several studies indicated extracellular signal-regulated kinases (ERKs), the phosphatidylinositol 3-kinase with its downstream effector AKT, and…

A 14-week, undergraduate-level Genetics and Population Biology course at Morgan State University was modified to include a demonstration of functional genomics in the research laboratory. Students performed a rudimentary sequence analysis of the "Caenorhabditis elegans" genome and further characterized three sequences that were predicted to encode…

A laboratory experiment is presented for the upper-level undergraduate physical chemistry curriculum in which the ternary phase diagram of water, 1-propanol and n-heptane is measured using proton nuclear magnetic resonance (NMR) spectroscopy. The experiment builds upon basic concepts of NMR spectral analysis, typically taught in the undergraduate…

The kinetics experiments on the ligand-C[subscript 60] exchange reactions on (dihapto-[60]fullerene) pentacarbonyl tungsten(0), ([eta][superscript 2]-C[subscript 60])W(CO)[subscript 5], form an educational activity for the inorganic chemistry laboratory that promotes graphical thinking as well as the understanding of kinetics, mechanisms, and the…

The purpose of this study was to investigate (a) what effect the use of interactive computer-based simulations (ICBSs), the use of laboratory inquiry-based experiments (LIBEs), and the use of combinations of an ICBS and a LIBE, in a conceptually oriented physics course, have on science teachers' beliefs about and attitudes toward the use of these…