This study investigates the factors driving football players with identical training experience and genetics to have dramatically different career paths. We studied two paired cases from a pool of 32 talented U-20 players who were twice World Champions. The first paired case is a set of monozygotic twins that played football for exactly the same…

Spinal Muscular Atrophy is a genetic, degenerative disorder, in which individuals become unable to engage in typical motor activities, including speech. The outcome for the most common type of SMA (Type 1), has previously been death before the age of 2, but new medical improvements are showing promising results for life longevity. Research has…

Dendritic regulatory BC1 RNA is a non-protein-coding (npc) RNA that operates in the translational control of gene expression. The absence of BC1 RNA in BC1 knockout (KO) animals causes translational dysregulation that entails neuronal phenotypic alterations including prolonged epileptiform discharges, audiogenic seizure activity in vivo, and…

We characterized the transcriptional response accompanying maintenance of long-term sensitization (LTS) memory in the pleural ganglia of "Aplysia californica" using microarray (N = 8) and qPCR (N = 11 additional samples). We found that 24 h after memory induction there is strong regulation of 1198 transcripts (748 up and 450 down) in a…

Two-dimensional nuclear magnetic resonance (2D NMR) techniques are regularly used for the determination of RNA structures. In an effort to introduce advanced level students who are generally not acquainted with or exposed to these techniques, this work, which has been designed as a practicum, utilizes a combination of 2D NMR techniques to help…

Basic quantitative and population genetics topics are typically taught in introductory plant breeding courses and are critical for success in upper-level study. Active learning, including simulations and games, may be useful for instruction of these concepts, which rely heavily on theory and may be more challenging for students. The statistical…

We examined the sophistication of middle school students' mechanistic explanations of genetics phenomena and how they interact with a technology-based explanation tool as they articulate and organize their ideas about the phenomena. We coordinated curriculum and assessment design frameworks to develop a middle school curriculum unit that engages…

In our technologically advanced society proficiency in mathematics is paramount to success in the science, technology, engineering, and mathematics (STEM) employment sector. Mathematics anxiety negatively affects an individual's physiological and cognitive functioning, which results in the individual obtaining lower achievement in mathematics. The…

The main purpose of this study was to design and verify the quality of an assessment aimed at diagnosing scientific misconceptions among students enrolled in 10th-grade biology subjects. A sample consisted of N=200 students from schools under the administration of the Office of Secondary Educational Service 31, Nakhon Ratchasima province. We…

Visual disengagement has been hypothesized as an endophenotype for autism. In this study we used twin modelling to assess the role of genetics in basic measures of visual disengagement, and tested their putative association to autistic traits in the general population. We used the Gap Overlap task in a sample of 492 twins. Results showed that most…

Following on earlier examinations of biology high school textbooks' handling of race, this study examines eleven biology textbooks, intended for US high school use and published between 2014 and 2019. It offers a close reading of these textbooks' treatment of four topics that have been associated with race: genetic disorders, human origins, skin…

In this paper we focused on university mathematics students' mental constructions on the concept limit of a sequence. The aim was to explore the nature of the mental constructions and to contribute to Action-Process-Object-Schema (APOS) theory in terms of instructional strategy for teaching limit of sequences. The belief that understanding…

An augmented reality (AR) application that complements a DNA precipitation experiment has been developed for use on mobile devices. The AR experience provides atomistic detail on the reasoning behind the experimental observations. The development of the application is described, as are the download data. In a pilot survey, the students were asked…

Advanced modeling of item response data through the item response theory (IRT) or item factor analysis frameworks is becoming increasingly popular. In the social and behavioral sciences, the underlying structure of tests/assessments is often multidimensional (i.e., more than 1 latent variable/construct is represented in the items). This review…

In the present study, language performance on standardized assessments (e.g., overall verbal performance, receptive and expressive vocabulary) and spontaneous language produced in play was compared between preschool-aged boys with autism spectrum disorder ([subscript n]ASD, n = 25) and boys with fragile X syndrome (FXS, n = 16). At the…