Background/purpose: This study aimed to identify the impact of teaching science based on John Zahorek's model on the acquisition of scientific concepts among seventh-grade female students. Materials/methods. It was based on the quasi-experimental method. The study participants, comprising 58 seventh-grade students, were intentionally selected from the Kasbah Zarqa District and divided into two groups. The sample was selected from among the two divisions by random appointment, where the experimental group consisted of 30 female students in the first division and the control group (28) female students in the second division. Results: After conducting statistical analysis through the SPSS program, the study showed a statistically significant effect at the significance level ([alpha]=0.05) of teaching science based on John Zahorek's model in acquiring scientific concepts among seventh-grade female students. Conclusion: The study recommended a set of recommendations, the most prominent of which are: Adopting John Zahorek's model as part of science education strategies in Jordanian schools.