Visual analysis is the predominant method of analysis in single-case research (SCR). However, most research suggests that agreement between visual analysts is poor, which may be due to a lack of clear guidelines and criteria for visual analysis, as well as variability in how individuals are trained. We developed a survey containing questions about…

Practitioners and policymakers often want estimates of the effect of an intervention for their local community, e.g., region, state, county. In the ideal, these multiple population average treatment effect (ATE) estimates will be considered in the design of a single randomized trial. Methods for sample selection for generalizing the sample ATE to…

In episodic memory research, there is a debate concerning whether decision-making in item recognition and source memory is better explained by models that assume all-or-none retrieval processes or continuous underlying strengths. One aspect in which these classes of models tend to differ is their predictions regarding the ability to retrieve…

The application of physico-chemical principles has been routinely used to explain various physiological concepts. The Nernst equation is one example of this, used to predict the potential difference created by the transmembrane ion gradient resulting from uneven ion distribution within cellular compartments and the interstitial space. This…

Background: Down Syndrome is the most common genetic disorder associated with intellectual and developmental disabilities. Research to improve health care outcomes in Down Syndrome lags significantly behind other disease categories. Among these reasons are funding, recruitment and availability of research studies being conducted. Methods: We…

Single-case experimental designs (SCEDs) are frequently used to evaluate whether a functional relation exists between interventions and student outcomes. A critical factor in decision making is the evaluation of graphical data, typically displayed in time-series graphs. Distortion in the graphical display of data can lead to invalid decisions on…

Common method variance refers to the amount of uncontrolled systematic error leading to biased estimates of scale reliability and validity and to spurious covariance shared among variables due to common method and/or common source employed in survey-based researches. As the extended use of self-report questionnaires is inevitable, numerous studies…

To initiate clinical research studies successfully and efficiently, it is critical to develop a strong, feasible, and well-written study protocol early in the start-up phase. The University of Minnesota's Clinical Research Support Center designed and implemented a structured Feasibility Review process in 2018 that addresses common start-up…

This Concise Review is an appraisal of contemporary research on teaching single-case experimental design (SCED) graphical creation published between 2017-2021. Recent work on SCED graphical creation is summarized and areas for future research are highlighted.

A latent variable modeling-based procedure is discussed that permits to readily point and interval estimate the design effect index in multilevel settings using widely circulated software. The method provides useful information about the relationship of important parameter standard errors when accounting for clustering effects relative to…

Understanding complex (social) phenomena benefits from combining different tools, perspectives, expertise, and experiences. Research designs that combine approaches are gaining in popularity. Carrying out research in interdisciplinary teams, however, is a challenging, high-investment activity. Unawareness of and reflecting on conflicting ways of…

Currently the design standards for single case experimental designs (SCEDs) are based on validity considerations as prescribed by the What Works Clearinghouse. However, there is a need for design considerations such as power based on statistical analyses. We compute and derive power using computations for (AB)[superscript k] designs with multiple…

Applied researchers faced with limited resources can utilize planned missing designs by incorporating missing data into their research design to collect more and higher quality data compared to a conventional experimental design. Two-method measurement planned missing designs (TMM-PMD) are a type of planned missing design whereby researchers…

Once research questions are posed, researchers must answer many a priori questions regarding research design before analysis can be performed and any conclusions can be made, including sample selection criteria, data collection method, model specification, analysis and estimation technique. The choices made by researchers along this forking path…

Over the past decade, transdisciplinary research has been faced with increasing demands by research policy and funding bodies to make its contribution to dealing with complex societal problems more transparent. In the literature, there is a range of methodological attempts to trace and describe the effects of transdisciplinary research, but these…