Integrating new synthetic methods and experimental techniques from the latest research reports into undergraduate laboratory experiments is of great significance, as it enables students to learn the cutting-edge technology of organic chemistry and cultivates their experimental skills and innovative thinking. In this study, an experiment on their…

A qualified teaching method is hard to achieve without traditional classroom lessons. For learning purposes, students need to interact and influence each other, like being part of an osmotic process. They need to learn in a stimulating environment, developing the ability to manage conflicts and to compare opinions. How can this be possible during…

A physical organic chemistry experiment is described for second-year college students. Students performed nucleophilic aromatic substitution (NAS) reactions on 5,10,15,20-tetrakis(2,3,4,5,6-pentafluorophenyl)porphyrin (TPPF[subscript 20]) using three different nucleophiles. Substitution occurs preferentially at the 4-position ("para")…

Laboratory courses are often designed using step-by-step protocols which encourage students to conduct experiments without thinking about what they are doing or why they are doing it. Such course design limits the growth of our students as scientists and can make it more difficult for a student to transition to the expectations of a research…

Routinely used in quantitative determination of various analytes, UV-vis spectroscopy is commonly taught in undergraduate chemistry laboratory courses. Because the technique measures the absorbance of light through the samples, losses from reflection and scattering by large molecules interfere with the measurement. To emphasize the importance of…

Lab-on-a-chip technology is brought into the classroom through development of a lesson series with hands-on practicals. Students can discover the principles of microfluidics with different practicals covering laminar flow, micromixing, and droplet generation, as well as trapping and counting beads. A quite affordable novel production technique…

Thin-layer chromatography (TLC) is one of the basic analytical procedures in chemistry and allows the demonstration of various chemical principles in an educational setting. An often-overlooked aspect of TLC is the capability to quantify isolated target compounds in an unknown sample. Here, we present a suitable route to implement quantitative…

The ability to develop, use, and refine models of experimental systems is a nationally recognized learning outcome for undergraduate physics lab courses. However, no assessments of students' model-based reasoning exist for upper-division labs. This study is the first step toward development of modeling assessments for optics and electronics labs.…

A surprising phenomenology from a traditional demonstration experiment in Geometrical Optics reveals here an interesting matter of discussion and analysis. Hence, the main focus of this paper is to observe and discuss such an innovative phenomenology.

Most biochemical transformations involve more than one substrate. Bisubstrate enzymes catalyze multiple chemical reactions in living systems and include members of the transferase, oxidoreductase, and ligase enzyme classes. Working knowledge of bisubstrate enzyme kinetic models is thus of clear importance to the practicing biochemist. However,…

Sign-tracking is a form of autoshaping where animals develop conditioned responding directed toward stimuli predictive of an outcome even though the outcome is not contingent on the animal's behavior. Sign-tracking behaviors are thought to arise out of the attribution of incentive salience (i.e., motivational value) to reward-predictive cues. It…

A new experiment based on phase inversion of Pickering emulsions was carried out in a physical chemistry course. The emulsions were stabilized by surfactant-modified SiO[subscript 2] particles. As the concentration of surfactant increased, the emulsions changed from oil-in-water type (O/W) to water-in-oil type (W/O) type, and then reverted to be…

Popular demonstrations commonly use stretched spandex fabric to illustrate the way in which curved spacetime mimics the force of gravity in general relativity. There are significant potential conceptual pitfalls to such an approach. In particular, it obscures the fact that most of what we ordinarily feel as gravity is due to the warping of time…

An understanding of buffers is important in a variety of chemistry subdisciplines, with relevant applications to the life sciences and health profession-related fields. Here, we describe the development and implementation of a lab that involves creating a buffer solution using baby wipes and deionized water. The goal of this lab was to emphasize a…

Purpose: The purpose of this study was to identify whether post-resistance exercise (REx) blood flow restriction (BFR) can elicit a similar acute training stimulus to that offered by either heavy REx or traditional low-load BFR REx. Method: Ten men completed trials with 30% one-repetition maximum (1RM) for 5 sets of 15 repetitions without BFR…