A facile, discovery-based experiment is described that introduces aliphatic substitution in an introductory undergraduate organic chemistry curriculum. Unlike other discovery-based experiments that examine substitution using two competing nucleophiles with a single electrophile, this experiment compares two isomeric, competing electrophiles…

Caffeine (1,3,7-trimethylxanthine) is an alkaloid stimulant that is popular in beverages. Fluorescence-coupled methods have been used to measure the caffeine content in coffee, tea, soft drinks, energy drinks, and cosmetics. In this experiment, we have developed a method for detecting caffeine in beverages utilizing the effect of the caffeine…

While structure-property relationships are commonly developed in applications of physical organic chemistry to real-world problems at the graduate level, they have not been generally emphasized in the undergraduate chemistry curriculum. For instance, the ability to modify the energy gap between the highest occupied molecular orbital (HOMO) and the…

Quantification of the many constituents that make up our food, whether they are desirable (vitamins, antioxidants, nutrients) or undesirable (pesticides, toxins), is one of the most practical applications of chemistry. In this study, kombucha, a popular fermented tea beverage, was analyzed using acid-base titration and high-performance liquid…

The second law of thermodynamics has various formulations. There is the "Clausius formulation," which can be stated in a very intuitive way: "No process is possible whose sole result is the transfer of heat from a cooler to a hotter body." There is also the "Kelvin-Plank principle," which states that "no cyclic…

The development of novel, high-yielding, and selective methodologies for the asymmetric synthesis of stereocenters is at the forefront of modern synthetic chemistry research. Organocatalysis can now be viewed as a viable alternative to the use of the sometimes toxic transition-metal catalysts. In this experiment, the simple synthesis of an achiral…

In this article, a bomb calorimeter experiment and subsequent calculations aimed at determining the strain energy of the cyclobutane backbone are described. Students use several butanol isomers instead of the parent hydrocarbons, and they manipulate liquids instead of gases, which makes the experiment much easier to perform. Experiments show that…

An undergraduate electrical conductivity measurement experiment in a physical chemistry lab and basic fitting procedures are presented that allow a characterization of micellar system of hexadecyltrimethylammonium bromide (cetyltrimethylammonium bromide, CTAB) in binary mixture of water and acetonitrile (ACN) as a cosolvent (10%, v/v) at 30.0 °C.…

Contribution: Prior studies comparing the effectiveness of different laboratory learning modes do not allow one to draw a universally valid conclusion, as other influences are mixed with the learning modes. In order to contribute to the existing body of work and to add another piece to the puzzle, this article demonstrates an improved methodology…

A two-week summer camp for high school students focused on sustainable polymers was developed and implemented. Students took part in experiments and interactive lessons that demonstrate polymer chemistry fundamentals alongside associated sustainability challenges and opportunities. For example, polymer concepts related to chemical properties…

COVID-19 pandemic is a disaster and prolonged crisis that has disrupted the education of millions of students with the closure of schools and universities in world-wide. This hard situation rises the necessity to develop a new teaching method to solve the problem of the massive disruption specially to practice work access. The goal of this paper…

Instructional labs are being transformed to better reflect authentic scientific practice, often by removing aspects of pedagogical structure to support student agency and decision making. We explored how these changes impact men's and women's participation in group work associated with labs through clustering methods on the quantified behavior of…

Incentivising has shown to improve participation in clinical trials. However, ethical concerns suggest that incentives may be coercive, obscure trial risks and encourage individuals to enrol in clinical trials for the wrong reasons. The aim of our study was to develop and pilot a discrete choice experiment (DCE) to explore and identify preferences…

To reduce the spread of COVID-19, most universities and colleges have moved all instruction temporarily online, including the instruction of chemistry laboratory courses. Teaching laboratory courses online while keeping students engaged is challenging and often leads to presenting prerecorded lab demonstrations, lab animations, or virtual…

This paper reports on a study aiming at examining the development of science process skills through the implementation of experiments in a science course which was performed in flipped classroom design. Flipped classroom model was implemented for a series of experimentation activities in a science classroom in which 38 science teacher candidates…