The development of renewable energy technology is increasing rapidly, one of which is the nanofiber membrane, which has the potential to be an innovative material for various applications, including renewable energy. Its utilization in learning, especially STEM-based approach, to improve students' understanding of renewable energy and its applications, is still limited. This study contributes by introducing a novel approach that integrates nanofiber membranes into STEM-based approach in current educational practices. This study aimed to describe and evaluate the effectiveness of STEM-based approach that integrates a nanofiber membrane to improve students' creative thinking skills on the topic of renewable energy. A quasi-experimental design with pre-test and post-test design was employed, involving 120 tenth-grade high school students. The findings indicated that implementing nanofiber membrane within STEM-based learning improved students' creative thinking skills compared to traditional teaching methods. In the experimental group, no students achieved medium-level n-gain, while 45.45% attained high-level n-gain. Conversely, in the control group, 13.64% of students had low-level n-gain, 86.36% reached medium-level, and none achieved high-level n-gain. This research highlights the importance of linking current technologies, such as nanofiber membranes, with classroom learning to enhance students' understanding of renewable energy and to prepare them for future sustainable development challenges.