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Direct linkSzeberenyi, Jozsef – Biochemistry and Molecular Biology Education, 2008
Mutational inactivation of a specific gene is the most powerful technique to analyze the biological function of the gene. This approach has been used for a long time in viruses, bacteria, yeast, and fruit fly, but looked quite hopeless in more complex organisms. Targeted inactivation of specific genes (also known as knock-out mutation) in mice is…
Descriptors: Genetics, Biology, Problem Solving, Science Instruction
Peppink, D.; Douma-Kloppenburg, D. D.; de Rooij-Askes, E. S. P.; van Zoest, I. M.; Evenhuis, H. M.; Gille, J. J. P.; van Hagen, J. M. – Journal of Intellectual Disability Research, 2008
Background: Determining the aetiology of intellectual disability (ID) enables anticipation of specific comorbidity and can thus be beneficial. Blood sampling, however, is considered stressful for people with ID. Our aim was to evaluate the feasibility of a non-invasive screening technique of nine microdeletions/duplications among adults with ID of…
Descriptors: Mental Retardation, Identification, Genetics, Sampling
Barnett, Kylie J.; Finucane, Ciara; Asher, Julian E.; Bargary, Gary; Corvin, Aiden P.; Newell, Fiona N.; Mitchell, Kevin J. – Cognition, 2008
The term synaesthesia has been applied to a range of different sensory-perceptual and cognitive experiences, yet how these experiences are related to each other is not well understood. Not only are there disparate types of synaesthesia, but even within types there are vast individual differences in the way that stimuli induce synaesthesia and in…
Descriptors: Individual Differences, Cognitive Ability, Sensory Experience, Perceptual Development
Price, Johanna R.; Roberts, Joanne E.; Hennon, Elizabeth A.; Berni, Mary C.; Anderson, Kathleen L.; Sideris, John – Journal of Speech, Language, and Hearing Research, 2008
Purpose: This study compared the syntax of boys who have fragile X syndrome (FXS) with and without autism spectrum disorder (ASD) with that of (a) boys who have Down syndrome (DS) and (b) typically developing (TD) boys. Method: Thirty-five boys with FXS only, 36 boys with FXS with ASD, 31 boys with DS, and 46 TD boys participated. Conversational…
Descriptors: Verbs, Nouns, Syntax, Down Syndrome
Kolata, Stefan; Light, Kenneth; Matzel, Louis D. – Intelligence, 2008
It has been established that both domain-specific (e.g. spatial) as well as domain-general (general intelligence) factors influence human cognition. However, the separation of these processes has rarely been attempted in studies using laboratory animals. Previously, we have found that the performances of outbred mice across a wide range of…
Descriptors: Experiments, Spatial Ability, Genetics, Animals
Dolan, Erin L.; Lally, David J.; Brooks, Eric; Tax, Frans E. – Science Teacher, 2008
In this article, the authors describe a large-scale research collaboration, the Partnership for Research and Education in Plants (PREP), which has capitalized on publicly available databases that contain massive amounts of biological information; stock centers that house and distribute inexpensive organisms with different genotypes; and the…
Descriptors: Investigations, Partnerships in Education, Internet, Educational Resources
Case, Emily – American Biology Teacher, 2008
Taxonomy, the identification, naming, and classification of living things, is an indispensable unit in any biology curriculum and indeed, an integral part of biological science. Taxonomy catalogues life's diversity and is an essential tool for communication. Textbook discussions of taxonomy range anywhere from three to eight domains of kingdoms.…
Descriptors: Textbooks, Biology, Classification, High Schools
Campbell, Dennis J.; Reilly, AmySue; Henley, Joan – Education and Training in Developmental Disabilities, 2008
This paper describes a research study that assessed young children with a low incidence disability, specifically Cri-du-Chat Syndrome (CDSC). A description of the concerns of assessing individuals with low incidence disabilities is described. Parent reports (using the Development Observation Checklist System) on the functioning of their children…
Descriptors: Disabilities, Genetic Disorders, Children, Adolescents
Gelinas, Jennifer N.; Tenorio, Gustavo; Lemon, Neal; Abel, Ted; Nguyen, Peter V. – Learning & Memory, 2008
Activation of Beta-adrenergic receptors (Beta-ARs) enhances hippocampal memory consolidation and long-term potentiation (LTP), a likely mechanism for memory storage. One signaling pathway linked to Beta-AR activation is the cAMP-PKA pathway. PKA is critical for the consolidation of hippocampal long-term memory and for the expression of some forms…
Descriptors: Persistence, Stimulation, Long Term Memory, Cognitive Processes
Phenotypical Characteristics of Idiopathic Infantile Nystagmus with and without Mutations in "FRMD7"
Thomas, Shery; Proudlock, Frank A.; Sarvananthan, Nagini; Roberts, Eryl O.; Awan, Musarat; McLean, Rebecca; Surendran, Mylvaganam; Kumar, A. S. Anil; Farooq, Shegufta J.; Degg, Chris; Gale, Richard P.; Reinecke, Robert D.; Woodruff, Geoffrey; Langmann, Andrea; Lindner, Susanne; Jain, Sunila; Tarpey, Patrick; Raymond, F. Lucy; Gottlob, Irene – Brain, 2008
Idiopathic infantile nystagmus (IIN) consists of involuntary oscillations of the eyes. The familial form is most commonly X-linked. We recently found mutations in a novel gene "FRMD7" (Xq26.2), which provided an opportunity to investigate a genetically defined and homogeneous group of patients with nystagmus. We compared clinical features and eye…
Descriptors: Visual Impairments, Eye Movements, Visual Acuity, Depth Perception
Chin, Christine; Teou, Lay-Yen – Journal of Biological Education, 2010
This study was carried out in the context of formative assessment where assessment and learning were integrated to enhance both teaching and learning. The purpose of the study was to: (a) identify pupils' ideas about biological inheritance through the use of a concept cartoon, pupils' drawings and talk, and (b) devise scaffolding structures that…
Descriptors: Formative Evaluation, Cartoons, Active Learning, Elementary School Science
Download full textSarpkaya, Ruhi – Educational Sciences: Theory and Practice, 2010
The aim of this research is to determine the factors affecting individual education demands at the entrance to university. The research is in survey model. The universe of the study consists of 1630 freshmen at the faculties and vocational schools of Adnan Menderes University, Aydin. 574 students from 7 schools were included in the sample. The…
Descriptors: Educational Demand, College Freshmen, Student Attitudes, Individual Differences
Nadolski, Jeremy; Smith, Lee Ann – PRIMUS, 2010
As technology and science advance, the boundary between the disciplines begins to blur, emphasizing that it is now, more than ever, a requirement to have a solid background in multiple fields to fully understand emerging scientific advances. As faculty, we need to equip our undergraduate students not only with an introduction to these modern…
Descriptors: Undergraduate Students, Student Research, Data Analysis, Teaching Methods
Nijmeijer, Judith S.; Hartman, Catharina A.; Rommelse, Nanda N. J.; Altink, Marieke E.; Buschgens, Cathelijne J. M.; Fliers, Ellen A.; Franke, Barbara; Minderaa, Ruud B.; Ormel, Johan; Sergeant, Joseph A.; Verhulst, Frank C.; Buitelaar, Jan K.; Hoekstra, Pieter J. – Journal of Child Psychology and Psychiatry, 2010
Background: Symptoms of autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) often co-occur. Given the previously found familiality of ASD symptoms in children with ADHD, addressing these symptoms may be useful for genetic association studies, especially for candidate gene findings that have not been consistently…
Descriptors: Body Weight, Social Behavior, Smoking, Autism
Sailors, Mary H.; Jackson, Andrew S.; McFarlin, Brian K.; Turpin, Ian; Ellis, Kenneth J.; Foreyt, John P.; Hoelscher, Deanna M.; Bray, Molly S. – Journal of American College Health, 2010
Objective: The Training Interventions and Genetics of Exercise Response (TIGER) study is an exercise program designed to introduce sedentary college students to regular physical activity and to identify genetic factors that influence response to exercise. Participants: A multiracial/ethnic cohort (N = 1,567; 39% male), age 18 to 35 years,…
Descriptors: Metabolism, College Students, Obesity, Exercise
