The final year of a biochemistry degree is usually a time to experience research. However, laboratory-based research projects were not possible during COVID-19. Instead, we used open datasets to provide computational research projects in metagenomics to biochemistry undergraduates (80 students with limited computing experience). We aimed to give…

Raman scattering spectroscopies are important analytical tools in modern chemistry. Here, we describe the construction of the unamplified Raman scattering analysis (URSA) instrument: an inexpensive, open-table Raman spectrometer that uses a 532 nm diode-pumped laser as a light source. Upon application of this spectrometer to DNA extracted from…

Innovative approaches to teaching genetics are essential for improving student engagement and comprehension in this challenging field. Laboratory-based instruction enhances engagement with the subject while fostering the development of practical competencies and deepening comprehension of theoretical concepts. However, constraints on time and…

Multicultural science education advocates that science education should pay attention to the uniqueness of students from different backgrounds. In developing instructional strategies, educators should respect students' differences according to their culture. However, In Taiwan, while Darwin's theory of evolution is taught in high school biology,…

Adaptive behaviour refers to the everyday skills that individuals are expected to have to function independently, based on their age and societal norms. Currently, we know little about the role of genetic and environmental factors in parent-rated adaptive behaviours in early infancy. The aim of this study was to investigate the aetiological…

Sleep problems are common in Rett syndrome and other neurogenetic syndromes. Actigraphy is a cost-effective, objective method for measuring sleep. Current guidelines require caregiver-reported bed and wake times to facilitate actigraphy data scoring. The current study examined missingness and consistency of caregiver-reported bed and wake times…

To assess whether genetic test results identifying the cause of a child's autism, when accompanied by other neurodevelopmental disorders (NDD), including intellectual disability, alter how parents perceive and treat their child. 28 parents of 22 individuals with autism (mean age: 15 years), usually with other NDDs, were interviewed after receiving…

3q29 deletion syndrome (3q29del) is associated with a significantly increased risk for neurodevelopmental and neuropsychiatric disorders. However, the full spectrum of behavioral phenotypes associated with 3q29del is still evolving. Individuals with 3q29del (n = 96, 60.42% male) or their guardian completed the Achenbach Child or Adult Behavior…

The 21st-century skills seek to develop learners who will be problem solvers in society. This paradigm shift requires the use of learner-centered strategies that emphasize collaborative problem-solving. To explore the effectiveness of such approaches, this study sought to determine how effective Wheatley's problem-centered approach would be in the…

The aim of this study is to determine the views of psychology graduate students on sexual crimes, crime sanctions and education. In the study, since the views of psychology graduate students on sexual crimes, crime sanctions and education were examined, a holistic single case study design was used. While determining the study group, convenience…

An explanation for the social dysfunction observed in Williams syndrome may be deficits in social cognition. This study explored aspects of social cognition in children with Williams syndrome with different genotypes. The 12 participants included one with a 1.1 Mb deletion that retained the GTF2IRD1, GTF2I, and GTF2IRD2 genes, seven with a 1.5 Mb…

The dopamine system has been implicated in decision-making particularly when associated with effortful behavior. We examined acute optogenetic stimulation of dopamine cells in the ventral tegmental area (VTA) as mice engaged in an effort-based decision-making task. Tyrosine hydroxylase-Cre mice were injected with Cre-dependent ChR2 or eYFP control…

Lab activities are characteristic of life science education. In the current study, we investigate whether pre-lab modules can improve students' understanding of the theories and experimental procedures associated with lab activities. Such effects were studied in context of an expository lab on gene mapping in biology undergraduate education. An…

This essay sheds light on the "father of epigenetics," Conrad Hal Waddington's (1905-1975) tacit critique of one of the most prominent biologists of the twentieth century, Julian Huxley's (1887-1975) theses concerning the evolutionary meaning and importance of learning and education for the human species. This topic has great…

Using data from 266 age- and sex-matched pairs of Jamaican children with autism spectrum disorder (ASD) and typically developing (TD) controls (2-8 years), we investigated whether glutathione S-transferase theta 1 ("GSTT1") modifies the association between blood manganese concentrations (BMC) and ASD. After adjusting conditional logistic…