A new undergraduate organic laboratory experiment has been developed and implemented for the Ugi three-component synthesis of the topical anesthetic lidocaine with excellent atom economy. Paraformaldehyde, diethylamine, and 2,6-dimethylphenyl isocyanide were combined and conveniently stirred at room temperature for a week in methanol with acetic…

General chemistry laboratories are a core requirement for nearly all STEM (Science, Technology, Engineering, and Mathematics) majors and have the greatest breadth in disciplines and audience of any STEM course at a university. A bioremediation Course-based Undergraduate Research Experience (CURE) for first-year undergraduate students was developed…

Course-based undergraduate research experiences (CUREs) are a promising approach for incorporating inquiry-based instruction into the undergraduate chemistry laboratory curriculum. This study used data from a national survey of inorganic chemistry faculty members (n = 142) to investigate CURE implementation in the inorganic chemistry instructional…

This study aimed to examine the impact of years of experience and field of expertise on the development of chemistry knowledge structures from STEM experts comprising 103 professors, 10 postdocs, and 146 doctoral students. Of these participants, 127 were specialized in chemistry and the rest were from various science and engineering disciplines.…

Mercury beating heart (MBH) is a well-known demonstration of redox processes. However, the development and application of the MBH system are significantly restricted due to its safety issues. Here, a direct current electric field-enabled gallium-based liquid metal heartbeat in a salt solution or alkaline solution is introduced as a demonstration…

Undergraduate organic chemistry laboratory courses act as a baseline for introductory scientific experimentation. These courses provide students with the knowledge and skills for their future careers. The traditional lab is conducted by providing a structured protocol of the experiment for the students to follow and reproduce the assigned task…

Recently, two-dimensional (2D) nanostructures, such as graphene and few-layer MoS[subscript 2], have been applied to wide fields based on their intriguing performances, and they contribute to developments of clean energy, biomedicine, and environmental protection. The synthesis of 2D nanostructures involves chemistry, materials, and…

Fieldwork is a meaningful and authentic learning experience that is rarely included in undergraduate chemistry courses. In this laboratory, we visited a hot spot of perfluoroalkyl acid (PFAA) contamination identified in 2012, in Binbrook, Ontario, Canada, a 1 h drive from the University of Toronto. The persistence and unique environmental…

Highlighting the interdisciplinary nature of research, we present a series of experiments for undergraduate lab courses that teach the principles of preparative ion exchange chromatography and flame emission spectroscopy. Through these inquiry-based experiments, the students learn about experimental design and instrument limitations, naturally…

Efforts to understand changes in teacher curricula following the adoption of reform-based standards, such as the "Next Generation Science Standards" (NGSS) remain incomplete and prior scholarship has identified several topics in the standards (e.g., nuclear chemistry and kinetics) that remain infrequently addressed in teachers'…

A laboratory activity was developed to teach freezing point depression and colligative properties to introductory-level chemistry students. The laboratory uses food-grade reagents and is delivered in two units that can be taught in a single 2 hour session or two separate sessions. The total cost of the consumables is 1 USD. In the first part of…

A new undergraduate organic laboratory experiment has been developed for amide bond formation between biorenewable 2-furoic acid and either of two substituted piperazines to prepare medicinally relevant amide products using a procedure with industrial significance. The reactions proceeded smoothly under ambient conditions using the combination of…

One way to preserve culture in education is through ethnoscience-based learning, especially in chemical materials linked to various fields of science in life, including social and cultural. Ethnoscience is a process of reconstructing indigenous science knowledge with scientific science. This research aims to explore trends in ethnoscience-based…

This paper presents an innovative teaching approach that integrates photoelectric technology with analytical chemistry instruction through inquiry-based learning (IBL), using cerium as a selected analyte. With the advancement of science and technology, a strong foundation of basic knowledge and methodologies is crucial in analytical chemistry…

Organic chemistry is a cognitively demanding subject with persistently low student achievement. This review aimed to identify instructional strategies and educational technologies used to improve learning outcomes in organic chemistry across educational levels and learning environments. A systematic review of 40 experimental studies (2014-2023)…