The effects of kinetic vs thermodynamic control on "endo"/"exo" stereoisomer ratios can be observed in a simple Diels-Alder reaction between "N"-phenylmaleimide and furan. The use of microwave-promoted synthesis affords the cycloadducts in yields ranging from 65-100%, employing reaction times of 1-10 min at…

SSurfactants or surface-active agents are interesting groups of compounds with characteristic structures, allowing them to decrease the surface tension. A surfactant consists of a hydrophilic head and a hydrophobic tail. Typically, surfactant molecules aggregate into micelles at the critical micelle concentration. In this work, the concept of…

A parallel series of general chemistry courses for Life Science Majors was created in an effort to support students and improve general chemistry outcomes. We created a two-quarter enhanced general chemistry course series that is not remedial, but instead implements several evidence-based teaching practices including Process Oriented Guided…

Approximations can help to orient the student in an organic chemistry laboratory. There the student needs to develop the solvent systems for the reaction and isolation of organic reactants and products. The adage "like dissolves like" helps in this regard, but this approach is vague and entirely qualitative. More quantitative approaches…

A symmetry activity using student-built models was developed in line with faculty-developed pedagogical goals and a collaborative learning framework. The activity took place in a 3-h laboratory portion of an upper-division inorganic chemistry course. It required students to identify symmetry elements for seven molecules using common 2D…

Cyclopropane can be hydrogenated to produce propane under moderately high temperatures ([tilde]175 [degrees]C). Using a nanoparticle palladium catalyst, undergraduate students can explore the reaction and draw conclusions regarding the conditions for reaction. When deuterium is used, conclusions pertaining to the reaction mechanism are possible.…

In a General, Organic, and Biological (GOB) Chemistry course designed for allied-health disciplines, new information builds on previous material. It is important for students to retain what they learn throughout the course and be able to integrate the material not only with material from other bioscience courses but also with the metabolism…

Laboratory chemical synthesis research typically lacks the preplanned hazard responses found in production-scale industrial laboratories. Chemical safety management is a known challenge in education-based facilities, which is concerning for academic and national laboratory environments working with inexperienced student researchers. At the…

An introductory experimental course to teach and assess basic organic synthesis and identification skills has been designed. The first work of this course, which is based on the well-known hydrazone formation reaction of benzaldehydes with Brady's reagent, is presented. The designed experiment has many advantages and perfectly matches the goal of…

Climate change is a critical scientific and social issue of our time, yet the topic is not frequently discussed by the general public. Additionally, misconceptions about the topic persist. One important aspect of climate change is the greenhouse effect. This activity adds a greenhouse gas discussion to an existing module about molecular shape and…

In this activity, students observe chemical and physical properties of elements using an online periodic table, where these properties were shown numerically and by colors. Then the elements were divided into metals, nonmetals, and metalloids, and their periodic properties were visualized using statistical concepts such as normality, kurtosis,…

Quinacridone red and violet are visually different colors, an observation confirmed by their visible reflectance spectra and CIE L*a*b* coordinates. However, their IR spectra are extremely similar. Though chemically identical, the two quinacridones are polymorphs. In this experiment, designed for and tested by nonscience majors, the pigments are…

Interfacial, or surface tension, is a significant topic in chemical education. This paper describes the directional motion of gallium-based liquid metal drops, resulting from a difference of interfacial tension across the drop. This demonstration can engage students in discovering the underlying chemical principles. A mechanism for the drop's…

This communication shows that although some textbooks do not discuss how to apply Raoult's law to electrolyte solutions, we should not ignore dissociation, and the van't Hoff factor must be considered.

Stereoselective reduction of ketones to alcohols using baker's yeast is a classic experiment in the undergraduate laboratory. Here we illustrate the reduction of racemic ethyl 2-fluoro-3-oxobutanoate to the corresponding alcohol using a set of four commercially available ketoreductases (KREDs). The reaction sets two stereocenters with four…