An inexpensive at-home quantitative analysis activity was developed for the determination of glucose in unknown samples using paper-based microfluidic devices. All of the materials and reagents for the activity fit in a small kit that was mailed to students. The only items students needed to supply were water and a smartphone. Microgram quantities…

The application of physico-chemical principles has been routinely used to explain various physiological concepts. The Nernst equation is one example of this, used to predict the potential difference created by the transmembrane ion gradient resulting from uneven ion distribution within cellular compartments and the interstitial space. This…

Redox reaction is a core concept in teaching and learning chemistry. This article explores a new method for balancing organic redox reactions that requires the balancing of both atoms and charges. The H+, O, H[subscript 2]O, and e- are used as balanced vehicles in two half reactions. A non-oxidation number approach can be applied to both molecular…

Morphology-dependent properties are significant in chemistry and material sciences. This laboratory experiment, designed for upper-division undergraduates in chemistry and related majors, emphasizes the concepts of the shape-controlled synthesis of crystal particles and the influences of crystal particle morphologies on their reaction…

Students quantified the protein content in beer, milk, powdered milk, and whey protein using the Bradford assay. The assay was carried out using absorbance measured at 595 nm (standard method) and 96-well-plate images (proposed method). They built analytical curves using bovine serum albumin (BSA) and casein and determined that protein type…

Oxidation number (ON) is taught as an electron-counting concept for redox reactions in chemistry curriculum. The molecular formula method, the Lewis formula method, and the structural formula method have all been used to determine ON. However, the task of assigning ON still poses problems for some teachers and students. This paper explores a new…

Discussions on decolonizing the curriculum are common in Humanities and Social Science Faculties but still rare in the Physical Sciences. In this commentary, we describe the work we have conducted to begin decolonizing and diversifying our undergraduate chemistry curriculum. We also discuss what it means to decolonize chemistry and reflect on why…

A central practice in the discipline of organic chemistry is the ability to solve certain fundamental problems, including predicting reactivity, proposing mechanisms, and designing syntheses. These problems are encountered frequently by both students and practitioners, who need to utilize vast amounts of content knowledge in specific ways to…

Introductory Chemistry is a foundation course that provides students with the basic knowledge and skills to enable them to be successful in the subsequent General Chemistry courses. Despite being an introductory course, it is still challenging for many students, making it ideal for the implementation of various pedagogical initiatives. One such…

This paper reports on a study that sought to improve pre-service science teachers' performance in the International Union of Pure and Applied Chemistry (IUPAC) nomenclature of aliphatic hydrocarbons using flipped classroom instructional approach (FCA). The study employed a single group pre- and post-test action research design. The sample size…

Starting with a double replacement reaction in alcohol between Ni(H[subscript 2]O)[subscript 6](NO[subscript 3])[subscript 2] and NaX, students exploit solubility differences to produce a solution of NiX[subscript 2] and a NaNO[subscript 3] precipitate. They then synthesize a bis(N,N-diethylethylenediamine) Ni(II) complex with chloride, bromide,…

Spectroscopic characterization of molecules is typically reinforced in the organic chemistry teaching laboratory via the analysis of reaction products by NMR and IR, and initial coverage of these topics can include experiments involving the identification of unknown compounds. To combine the unknown identification component with common laboratory…

Science, technology, engineering, and mathematics (STEM) courses are considered to be challenging for students and may present unique challenges for each domain. This study addresses a gap in the research literature by investigating the challenges students face in general and organic chemistry lecture courses. Students provided information…

A discovery-based experiment for the synthesis of arylpropiolic acids via carboxylation of arylacetylenic Grignard reagents was developed. This experiment shows the "dual utility" of Grignard reagents. In the synthesis of arylpropiolic acids reported here, we have demonstrated the use of a Grignard reagent as a base in a "Grignard…

Electrochemical impedance spectroscopy (EIS) is a rapid and powerful method for evaluating the pore structure of membranes. However, the application is limited due to the lack of appropriate training of engineers in electrochemistry and materials engineering. The introduction of laboratory practices can effectively improve the understanding of…