In order to improve the accessibility and user friendliness of an accurately pretrained stacking ensemble machine learning regressor used to predict sulfate levels (mg/L) in Acid Mine Drainage (AMD), a Graphical User Interface (GUI) was developed using Python by combining human input with ChatGPT and deployed in the Jupyter Notebook environment.…

The utilization of virtual compound libraries and virtual screening has become a routine method in drug discovery and has accelerated the research of pharmacy and translational medicine. With the development of computer-aided drug design (CADD), it is essential to incorporate virtual experiments into the education of medicinal chemistry. Herein,…

We describe a three-day advanced organic laboratory experience that includes the solid-phase synthesis of an unknown three amino acid polypeptide for junior/senior undergraduate chemistry majors. Students conduct a series of 1D and 2D NMR experiments (HSQC, HMBC, TOCSY) and analyze the data to identify the side chain residues of the peptide and…

Triterpenic acids (TA), a class of triterpenoids, are widely distributed as secondary metabolites in plants. They have a pentacyclic structure and show high structural diversity. In this work, a simple but efficient method for extraction and detection of TA derivatives from apple peels is described. The method is technically straightforward and…

In this in-class activity, organic chemistry undergraduates try to place an assortment of molecules in chronological order from oldest to most recently synthesized. In the students' first attempt, they use their knowledge of reactions and synthesis to analyze the organic compounds for their structural complexity. Before a second attempt, the names…

Many students find introductory general chemistry courses difficult because they feel alienated by traditional approaches to teaching and learning. This can become particularly problematic in laboratory sessions where students simply follow processes and procedures that students can view as being mundane and lacking creativity. Contextualised…

Universities tend to focus on the hard skills required within disciplines, with a general lack of focus on the teaching of soft skills, specifically in the hard sciences, while a graduate with good attributes ought to have both. There is an uncertainty over whose responsibility it is to teach soft skills between industry and universities, with the…

This investigation of student and instructor representations of molecular orbitals (MOs) uses the knowledge from a community of practice to build collective pedagogical content knowledge of student understanding of molecular orbital representations in the foundation-level inorganic chemistry course. Participants were asked to sketch the bonding…

We report the design of a low-cost electrochemical workstation and open-source graphical user interface capable of performing a variety of electrochemical methods in an undergraduate teaching laboratory. The instrument--based on the popular Arduino microcontroller board--can be constructed from common components for $40 USD. The modular design of…

Research from other STEM disciplines suggests that a systems thinking approach can motivate students to learn content meaningfully and in a way that empowers them to use their knowledge to benefit the world around them. However, systems thinking is not currently widespread in chemistry education. As instructors' beliefs influence their classroom…

Academic integrity is often a concern instructors have when teaching, with past research indicating the classroom environment is one of the largest factors in determining students' likelihood to cheat. In this commentary, we intend to start a dialogue with instructors regarding the importance of creating a classroom environment that values…

There is a gap between the importance of certain archeological material sources and their perception, both by professionals and by the general public. Textiles, for example, are essential to understanding practices that marked daily life and rituals in the past, but they have often been extremely degraded over time, particularly in temperate…

A very simple and color-observable homemade Raman spectroscope with easy preparation is introduced by simply adding low-cost components (a transmission diffraction grating sheet, a magnifying glass, a paper mask, and a DPSS laser pointer module) to a consumer digital camera. The Raman spectral images and profiles of cyclohexane, carbon…

A series of distinctive gap-fill activities were designed to provide practice and test students' knowledge in retrosynthetic analysis. Developed and tested during the COVID-19 pandemic, the activities allow students to work through authentic multistep syntheses of various organic target molecules. Students were asked to identify appropriate RSA…

Water electrolysis, a well-known and simple experiment, confirms that a water molecule comprises hydrogen and oxygen atoms. In this experiment, hydroxide or hydrogen ions generated from each electrode were identified using an indicator based on the assumption that electrodes, electrolytes, and indicators do not participate in the water…