The blended learning approach for course delivery using the Moodle Learning Management System (LMS) is used for online course delivery at Makerere University Business School (MUBS). The study establishes learner views about e-learning and presents a blended learning approach with online assignment and discussion forum for a systems analysis and design course. The course was administered using the Moodle open source learning management system. Questionnaires were administered to a class of 39 students to conduct course evaluation after introducing students for the first time to e-learning. The evaluation results showed that students strongly recommended the e-learning approach for postgraduate studies with an acceptance rate of 80%. Students expressed a number of benefits from online classes, including: easy provision of lecture materials; ease of coursework administration; efficient and effective way of teaching; user friendly learning environment; cost-effective way of studying; useful interactive discussions; flexibility in learning; and a good avenue of learning computerized system. The students mentioned some challenges that should be addressed by institutions for effective e-learning to take place. These include: accessible Internet; availability of computer equipment and e-learning integration in other courses. Future research is needed to experiment with e-learning implementation in a large class of 200 students or more.