We describe an experiment for the undergraduate organic laboratory curriculum in which 2-bromoacetophenone is converted to 2-fluoroacetophenone using a solid-phase nucleophilic fluorine source. The experiment introduces students to the utility of solid-phase reagents in organic synthesis, to NMR-active nuclei other than [to the first power]H…

A microscale experiment is presented in which cyclohexene is dihydroxylated under three sets of conditions: epoxidation-hydrolysis, permanganate oxidation, and the Woodward dihydroxylation. The products of the reactions are determined by the use of thin-layer chromatography. Teams of students are presented with proposed mechanisms for each…

In this article a potentiometric method for reducing sugar quantification is described. Copper(II) ion reacts with the reducing sugar (glucose, fructose, and others), and the excess is quantified using a copper wire indicator electrode. In order to accelerate the kinetics of the reaction, working conditions such as pH and temperature must be…

An undergraduate biochemistry laboratory experiment that will teach the technique of fluorescence resonance energy transfer (FRET) while analyzing protein-induced DNA bending is described. The experiment uses the protein TATA binding protein (TBP), which is a general transcription factor that recognizes and binds specific DNA sequences known as…

For curriculum content-related reasons, inquiry activities can be difficult in classrooms unless the activities are approached in a manner that makes variations among student group findings understandable in the context of the study. Studies of individual animals and plant reactions to stimuli, such as insect exploratory behavior, allow the…

Using an easy-to-make cylindrical resonator, students can measure the speed of sound in a gas, u, with sufficiently high precision (by locating standing-wave Lissajous patterns on an oscilloscope) to observe real gas properties at one atmosphere and 300 K. For CO[subscript 2] and SF[subscript 6], u is found to be 268.83 and 135.25 m s[superscript…

Nowadays, outreach labs are important informal learning environments in science education. After summarizing research to goals outreach labs focus on, we describe our evidence-based gene technology lab as a model of a research-driven outreach program. Evaluation-based optimizations of hands-on teaching based on cognitive load theory (additional…

Are you interested in using argument-driven inquiry for high school lab instruction but just are not sure how to do it? You are not alone. This book will provide you with both the information and instructional materials you need to start using this method right away. "Argument-Driven Inquiry in Biology" is a one-stop source of expertise,…

Learning the concept of perimeter and area is not easy for students in grade 3 of primary school. A common mistake is that students think that if the area is the same, the perimeter also has to be the same. It is difficult for them to understand that for a given area, there are many possibilities of perimeter and vice versa. When student are not…

The meaning of fractions with integer multiplication is something that is difficult to understand by students. They tend to think that the product it produces a larger number, while the multiplication of fractions with integers, the result can be any number larger or smaller. This study is a research design that aims to develop a local…

Background: One of the unfortunate side effects of the industrial revolution has been the constant assault of the environment with various forms of pollution. Lately, this issue has taken a more critical dimension as prospects of global climate change and irreversible ecosystem damage are becoming a reality. Purpose: College graduates (especially…

Primary literature is our main mode of communication in the sciences. As such, it is important for our undergraduates in the discipline to learn how to read primary literature. Incorporating primary literature into undergraduate science courses is often difficult because students are unprepared to comprehend primary articles. Learning to read and…

Practical skills and competencies are critical to student engagement and effective learning in laboratory courses. This article describes the design of a yearlong, stand-alone laboratory course--the Biotechniques Laboratory--a common core course in the second year of all our degree programs in the biological sciences. It is an enabling,…

Two experiments using the science topics of Magnetism and Light were conducted with younger learners (Year 5) who had no prior knowledge of the topics, and older learners (Year 6) who had studied the topics previously. Half of the learners were presented the information in auditory form only while the other half were presented the auditory…

The speed of sound is a physical property that can be measured easily in the lab. However, finding an inexpensive and intuitive way for students to determine this speed has been more involved. The introduction of affordable consumer-grade high-speed cameras (such as the Exilim EX-FC100) makes conceptually simple experiments feasible. Since the…