A major challenge when designing new experiments for the general chemistry laboratory is introducing students to the necessary techniques while keeping the experiment engaging and accessible. This work presents a new multiweek activity designed to introduce students to advanced instrumentation in the form of high-performance liquid chromatography…

Chirality continues to intrigue scientists because of its implications in various scientific areas, including the long-unsolved question of its development and link with the origin of life. Chirality plays a significant role in medicine with the advent of chiral drugs and the consequent importance of asymmetric synthesis. For many undergraduate…

The Kigali Amendment introduced a new family of chemical compounds, which do not contribute to stratospheric ozone depletion but present a high global warming potential, under the watch of the Montreal Protocol in 2016. Earlier this year, a press note from the World Meteorological Organization entitled "Ozone layer recovery is on track,…

An integrated laboratory experience in X-ray photoelectron spectroscopy (XPS) is designed for undergraduate and graduate students in chemistry, materials science, and other related fields. Focusing on ubiquitous Si, Cu, and their common oxides, students are guided to characterize a series of standard materials by XPS to understand the fundamentals…

In 2002, the Swedish National Food Agency and researchers from Stockholm University made an announcement regarding the presence of acrylamide in carbohydrate-rich foods that are exposed to high temperatures, with cereals, potatoes, and coffee possibly being the most significant sources of ingestion. Although limited data are available on assessing…

Microfluidic-based ultramicroscale chemistry experiments involve the manipulation and consumption of reagents on a microliter or submicroliter scale in a microfluidic device. This article presents the pedagogical functions of microfluidic systems, including green chemistry education, stimulation of students' interest in learning about chemistry,…

Under the appropriate conditions, oscillatory chemical reactions have the capacity to generate chemical waves and spatial patterns. Among these structures, Turing patterns are a distinct class that, to date, has not been commonly demonstrated in a classroom environment. We present here a novel, practical procedure for the demonstration of Turing…

The area of application of electrospray ionization mass spectrometry (ESI-MS), usually coupled with liquid chromatography, seems to be much larger than those of any other ionization method. It gives rise to the demand for new teaching methods that would effectively help students to master the principles of working with and making full use of the…

Experiments that explore quantum principles while utilizing and reinforcing previous synthesis skills are excellent for engaging students and promoting the interconnected nature of chemistry. This experiment utilizes sophomore-level organic synthesis techniques to have students produce their own "meso" substituted porphyrins. The UV-vis…

Paal--Knorr reactions are a classical method for synthesizing pyrroles, using 1,4-dicarbonyl compound and amine as reactants. It has the characteristics of green chemistry, as only two molecules of water are lost. In this teaching and learning experiment, 2,5-hexanedione and 4-"tert"-butylaniline were used to synthesize…

Student engagement in evidence-based argumentation plays a central role in science education. These skills can be developed when identifying organic molecules from the spectroscopic data. Molecular structural analysis fosters deep procedural knowledge, as it involves (i) flexibly applying a set of procedures to extract information from spectra,…

Colloidal stability is one of the most important criteria in the application strategy of colloidal nanoparticles in the continuous phase. The branches include ecology, involving coagulation as a purification method; medicine as nanocarriers; biology as blood coagulation, etc. A chemist versed in these concepts is a high-performing chemist in…

Molecular representations that show chemical bonding are ubiquitous in general and organic chemistry. These help in communicating chemistry concepts that are fundamental to understanding "how" and "why" molecules interact. The goal of this dissertation work is to offer an evidence-based report on the affordances and limitations…

A fast, operationally simple, and reproducible synthetic protocol for anthraquinone dyes (AQDs), suitable for upper-division undergraduate industrial and organic chemistry laboratory courses, has been developed. This experiment is composed of three stages; the first step deals with the synthesis of AQDs, followed by a purification step, and…

Many disciplines have used concept inventories (CI) to better understand the alternative ideas held by students. Administering a CI at both the beginning and the end of the semester can yield much information. For example, a comparison of both pre- and post-test responses can help determine if specific gains in student learning were met. In this…